Work

Refractory Periorbital Necrobiotic Xanthogranuloma Treated With Plasma Cell‐Directed Therapy

Year: 2026

Type: article

Abstract: A 57-year-old female with a reported history of isolated neutropenia presented with 3 years of progressive bilateral vision loss and 4 months of a rapidly growing plaque on her FIGURE 1 Physical examination demonstrated necrobiotic xanthogranuloma skin lesions of the patient's left eyelid (A) and left upper thigh (C).MRI of the orbits demonstrated a left superomedial preseptal mass (B) that resolved after treatment with plasma cell-directed therapy (D).left eyelid (Figure 1A ).MRI of the orbits revealed a 1.4 cm left superomedial preseptal mass with retroseptal extension (Figure 1B ).On pathological analysis after left anterior orbitotomy, biopsy

Source: eJHaem

DOI: 10.1002/jha2.70223

Authors: Aaron Trando, Ah‐Reum Jeong, Aaron M. Goodman

Institution: University of California San Diego

Language: English

Topic: Multiple Myeloma Research and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,860