Work

Fusariacumines A C, indole alkaloids from Fusarium acuminatum J207-2 with antibacterial activity

Year: 2026

Type: article

Abstract: In order to search for antibacterial agents against kiwi plant pathogen Pseudomonas syringae pv. actinidiae (Psa), a Gram-negative bacterium that causes kiwi bacterial canker, three new indole alkaloids, fusariacumines A–C ( 1 – 3 ), together with two known ones ( 5 and 6 ) have been isolated from a kiwi plant-associated fungus Fusarium acuminatum J207–2. Their chemical structures were determined by spectroscopic methods (1D, 2D NMR and HRESIMS). Compounds 1 and 3–5 exhibited moderate anti-Psa activity with minimum inhibitory concentration (MIC) values ranging from 32 to 128 μg/mL.

Source: Phytochemistry Letters

DOI: 10.1016/j.phytol.2026.104120

Authors: Hua Guo, Quan-Ping Diao, Tao Feng, Juan He

Institutions: Anshan Normal University, South Central Minzu University

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Zero hunger

Open Access status: hybrid

Estimated APC paid: $3,520