Commensal-derived trehalose monocorynomycolate triggers γδ T cell-driven protective ocular barrier immunity
Year: 2026
Type: article
Source: Immunity
Authors: Xiaoyan Xu, Yannis E. Rigas, Mary J. Mattapallil, Jing Guo, Keiko Sakamoto, Keisuke Nagao, Vijayaraj Nagarajan, Eric Bohrnsen, Crystal Richards, Akriti Gupta, Guillaume Gaud, Paul E. Love, Timothy Jiang, Amy Zhang, Biying Xu, Zixuan Peng, Yingyos Jittayasothorn, Mary A. Carr, M. Teresa Magone, Nathan T. Brandes, Jackie Shane, Benjamin Schwarz, Anthony J. St. Leger, Rachel R. Caspi
Institutions: National Institutes of Health, National Eye Institute, University of Pittsburgh, Stanford Medicine, Stanford University, National Institute of Arthritis and Musculoskeletal and Skin Diseases, University of Mississippi Medical Center, National Institute of Allergy and Infectious Diseases
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
Funders: U.S. Department of Health and Human Services, Eye and Ear Foundation of Pittsburgh, Research to Prevent Blindness, National Institutes of Health, School of Medicine, Stanford University, National Heart, Lung, and Blood Institute, National Eye Institute, National Cancer Institute, National Institute of Allergy and Infectious Diseases, NHLBI Division of Intramural Research
Awards: G138377103, G2902104123, Genetic, Cellular and Molecular Mechanisms in Autoimmunity to Retina, Interdisciplinary Visual Sciences (IVS) Training Program, Core Grant for Vision Research, Defining bacterial members of the ocular surface microbiome and assessing stability over time, Understanding the microbial requirements for colonization and immunogenicity of commensal bacteria at the ocular surface
OpenAlex ID: W7124828601