Work

Antimicrobial activity of native Lactobacillus cell-free supernatant against diarrheagenic Escherichia coli isolated from hospitalized patients in northern Iran

Year: 2026

Type: article

Abstract: BACKGROUND AND AIMS: Antibiotic resistance is a growing concern in the fight against Escherichia coli, a pathogen that causes various intestinal diseases. The present study explores the antibacterial effect of lactobacillus on E. coli pathotypes. METHODS: Inpatients stool samples were collected and E. coli pathotypes were identified. The antibacterial effect of five Lactobacillus on the pathotypes was investigated by broth microdilution and well diffusion methods. RESULTS: The CFS of L. plantarum, L. rueteri and L. acidophilus had the greatest antibacterial effect. CONCLUSION: Postbiotics have shown significant bactericidal effects against E. coli pathotypes. Their bactericidal effect can prevent the colonization of these pathotypes in hospitalized patients.

Source: Indian Journal of Medical Microbiology

DOI: 10.1016/j.ijmmb.2026.101063

Authors: Farzaneh Rafie Sedaghat, Ali Mojtahedi, Meysam Hasannejad-Bibalan, Tofigh Yaghubi Kalurazi, Tohid Samadpour Zahmat-dar

Institutions: Guilan University of Medical Sciences, Iran University of Medical Sciences, Islamic Azad University Rasht Branch

Language: English

Topic: Probiotics and Fermented Foods

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,210