Work

Open synovectomy for treatment of tenosynovial giant cell tumors of the knee in children

Year: 2025

Type: article

Abstract: We present seven pediatric cases of open knee synovectomy for tenosynovial giant cell tumor (TGCT)-four diffuse (D-TGCT) and three nodular (N-TGCT). The mean patient age at surgery was 11.3 ± 4.77 years. Five cases were diagnosed and treated within the past 2 years, indicating an unusually high incidence of TGCT in our institution. Subtotal synovectomy was performed through an anterior parapatellar approach, while posterior lesions were accessed between the semitendinosus and medial gastrocnemius muscles. The mean follow-up period was 39 ± 62.3 months (minimum 12 months). No recurrences were detected on follow-up MRI. Six patients regained full knee range of motion, and none exhibited postoperative monoarthritis. These favorable outcomes support open synovectomy as a safe and effective treatment for knee-localized D-TGCT and N-TGCT, especially in cases with posterior or retrocondylar localization.

Source: Journal of Surgical Case Reports

DOI: 10.1093/jscr/rjaf1113

Authors: Hristo Georgiev, Nia Gecheva, Alexander Gerchev, Stefan Tserovski, Daniel-Neno Nenov, Kircho Patrikov

Institution: Medical University of Sofia

Language: English

Topic: Musculoskeletal synovial abnormalities and treatments

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000