Year: 2026
Type: article
Abstract: Pine wilt disease (PWD), caused by Bursaphelenchus xylophilus, is driven by a tri-component system involving the pinewood nematode, Monochamus spp. beetle vectors, and susceptible pine hosts. Chemical control remains a scenario-dependent option for emergency suppression and high-value protection, but its deployment is constrained by strong regional regulatory and practical differences. In Europe (e.g., Portugal and Spain), field chemical control is generally not practiced; post-harvest phytosanitary treatments for wood and wood packaging rely mainly on heat treatment, and among ISPMs only sulfuryl fluoride is listed for wood treatment with limited use. This review focuses on recent progress in PWD chemical control, summarizing advances in nematicide discovery and modes of action, greener formulations and delivery technologies, and evidence-based, scenario-oriented applications (standing-tree protection, vector suppression, and infested-wood/inoculum management). Recent studies highlight accelerated development of target-oriented nematicides acting on key pathways such as neural transmission and mitochondrial energy metabolism, with structure–activity relationship (SAR) efforts enabling lead optimization. Formulation innovations (water-based and low-solvent products, microemulsions and suspensions) improve stability and operational safety, while controlled-release delivery systems (e.g., micro/nanocapsules) enhance penetration and persistence. Application technologies such as trunk injection, aerial/Unmanned aerial vehicle (UAV) operations, and fumigation/treatment approaches further strengthen scenario compatibility and operational efficiency. Future research should prioritize robust target–mechanism evidence, resistance risk management and rotation strategies, greener formulations with smart delivery, and scenario-based exposure and compliance evaluation to support precise, green, and sustainable integrated control together with biological and other sustainable approaches.
Source: Forests
DOI: 10.3390/f17010137
Authors: Die Gu, Taosheng Liu, Zhenhong Chen, Yanzhi Yuan, Lu Yu, Shan Han, Yonghong Li, Xiangchen Cheng, Yu Liang, Laifa Wang, Xizhuo Wang
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,137
OpenAlex ID: W7124919708