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An unexpected finding of large bowel obstruction from colonic diaphragm disease following prolonged use of indomethacin

Year: 2025

Type: article

Abstract: Colonic stricture leading to large bowel obstruction is an uncommon presentation to the emergency department. Strictures are commonly established secondary to diverticular disease, inflammatory bowel disease, malignancy or ischaemic/infective colitis. The formation of a colonic stricture secondary to the chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) is an unusual finding. We present a case of a 48-year-old lady who presented with a large bowel obstruction secondary to NSAID-induced right colonic stricture in a patient who was initially thought to have an index presentation of colonic Crohn's disease.

Source: Journal of Surgical Case Reports

DOI: 10.1093/jscr/rjaf1074

Authors: Isabella Zappala, Joseph Do Woong Choi, Evangeline Woodford, Raymond Kwok, Peter Dutton

Institutions: Westmead Hospital, The University of Sydney

Language: English

Topic: Intestinal and Peritoneal Adhesions

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000