Uterine carcinosarcoma due to foreign body (migrated intrauterine device): an extremely rare etiology of gynecological neoplasm
Year: 2026
Type: article
Study design: Case Report
Abstract: INTRODUCTION: Uterine carcinosarcomas are extremely rare gynecological neoplasms. The coexistence of intraabdominal foreign bodies, such as migrated IUDs, and uterine neoplasms, particularly carcinosarcomas, represents a significant clinical challenge and infrequent association. Chronic inflammation associated with foreign bodies can act as a cofactor in carcinogenesis and explain the appearance of these tumors. CASE PRESENTATION: A 65-year-old woman with a history of cesarean section, presented to the emergency department with a 5-day complaint of abdominal pain, nausea and constipation. An abdominal CT scan was performed, revealing a left parauterine mass containing a migrated intrauterine device (Lippes's loop) with a transition zone in the sigmoid colon. The patient was taken to exploratory laparotomy, where a subtotal hysterectomy and left salpingo-oophorectomy were performed. Pathology report showed uterine carcinosarcoma. DISCUSSION: This case exemplifies a rare clinical presentation of uterine neoplasm secondary to the presence of a foreign body (Lippes's loop), debuting with bowel obstruction. CONCLUSION: Uterine neoplasm secondary to foreign bodies are very rare clinical entities, and its pathophysiological mechanisms have not been fully understood. Particularly, uterine carcinosarcomas are a subgroup of these malignancies with a more aggressive behavior and poor oncological prognosis. Early diagnosis and prompt surgical management are the cornerstones of management.
Source: BMC Surgery
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,090
OpenAlex ID: W7124974121