Work

Co-occurrence of Vogt–Koyanagi–Harada disease, diabetic retinopathy, and advanced chronic kidney disease: a case report

Year: 2026

Type: article

Abstract: Objective: This study aimed to report a case of Vogt-Koyanagi-Harada (VKH) disease in a 53-year-old man with renal failure and diabetes, highlighting the challenges in diagnosing VKH amidst complex systemic comorbidities. Methods: A case report was conducted through a retrospective review of the patient's medical history, clinical presentations, diagnostic workup, and treatment course. Results: A 53-year-old man with renal failure, hypoalbuminemia, and diabetes presented with blurred vision. Initial findings included bilateral serous retinal detachment with subretinal septa, choroidal thickening, and left eye vitreous hemorrhage, without anterior chamber inflammation. Subsequent anterior segment inflammation and a positive response to combined corticosteroids and adalimumab confirmed VKH. Conclusion: This case underscores the diagnostic complexity of VKH in patients with multiple systemic conditions. Corticosteroid management in such individuals requires meticulous attention, emphasizing the need for close monitoring of blood glucose and overall systemic status during treatment.

Source: Frontiers in Medicine

DOI: 10.3389/fmed.2026.1733153

Authors: Yutong Huang, Yifei Wang, Qian Ren

Institutions: Hebei Medical University, First Hospital of Shijiazhuang

Language: English

Topic: Ocular Diseases and Behçet’s Syndrome

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801