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Hearing loss in the young-old is associated with increased risk for Alzheimer's disease and vascular dementia

Year: 2026

Type: article

Abstract: Hearing loss is a risk factor for dementia, but dementia subtypes underlying this association and effect modifiers are unknown. Using data collected from 2000 Framingham Heart Study participants we found that hearing loss increases risk for Alzheimer's disease and vascular dementia in participants aged 60-70 years ("young-old") at time of hearing assessment (Alzheimer's disease: HR 1.46[CI 1.07-2.0] p = 0.017; vascular dementia: HR 2.08[CI 1.22-3.56] p = 0.007). Longer duration of hearing loss determines increased risk for Alzheimer's disease and vascular dementia, and screening and intervention for hearing loss from mid-life may help reduce dementia.

Source: Journal of Alzheimer s Disease

DOI: 10.1177/13872877251407211

Authors: Lily Francis, Alexa Beiser, Sophia Lu, Sharon G Kujawa, Nancy Heard-Costa, Francis B Kolo, M Ilyas Kamboh, Rebecca Bernal, D Bradley Welling, Richard L Alcabes, Jayandra J Himali, Sudha Seshadri

Institutions: The University of Texas at San Antonio Health Science Center, Boston University, Framingham Heart Study, Massachusetts Eye and Ear Infirmary, Harvard University, University of Pittsburgh

Language: English

Topic: Hearing Loss and Rehabilitation

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Institutes of Health, National Institute on Aging

Awards: G2630878680, G343469054, Temporal Trends, Novel Imaging and Molecular Characterization of Preclinical and Clinical Alzheimer's Disease in the Framingham Cohorts, G511441455, Preclinical AD: Correlates of Amyloid, Tau PET and fcMRI in Framingham Gen 3 Young Adults, G553387340, G6273472674, G6373631636, The Framingham Heart Study, G892234758, G8989874213

OpenAlex ID: W7124990339

FWCI:

Cites: 27

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