Year: 2026
Type: article
Abstract: Tooth developmental anomalies are a group of disorders caused by unfavorable factors affecting the tooth development process, resulting in abnormalities in tooth number, structure, and morphology. These anomalies typically manifest during childhood, impairing dental function, maxillofacial development, and facial aesthetics, while also potentially impacting overall physical and mental health. The complex etiology and diverse clinical phenotypes of these anomalies pose significant challenges for prevention, early diagnosis, and treatment. As they usually emerge early in life, long-term management and multidisciplinary collaboration in dental care are essential. However, there is currently a lack of systematic clinical guidelines for the diagnosis and treatment of these conditions, adding to the difficulties in clinical practice. In response to this need, this expert consensus summarizes the classifications, etiology, typical clinical manifestations, and diagnostic criteria of tooth developmental anomalies based on current clinical evidence. It also provides prevention strategies and stage-specific clinical management recommendations to guide clinicians in diagnosis and treatment, promoting early intervention and standardized care for these anomalies.
Authors: Jingxian Zhu, Mian Wan, Xiaohong Duan, Zhipeng Fan, Yao Sun, Xudong Wang, Shuguo Zheng, Liwei Zheng, Qinglin Zhu, Dong Chen, Jiewen Dai, Dong Han, Miao He, Cui Huang, Yuegui Jiang, Zhonglin Jia, Yihuai Pan, Yongchu Pan, Tiemei Wang, Wenmei Wang, Baoshan Xu, Wei Yin, Tingting Zhang, Yanli Zhang, Zhenjin Zhao, Zhuan Bian, Yaling Song
Institutions: Wuhan University, Sichuan University, State Key Laboratory of Oral Diseases, Air Force Medical University, Capital Medical University, Tongji University, Shanghai Stomatological Hospital, Shanghai Jiao Tong University, Shanghai Ninth People's Hospital, Peking University, Zhengzhou University, First Affiliated Hospital of Zhengzhou University, Xi'an Jiaotong University, Wenzhou Medical University, Nanjing Medical University, Nanjing University, Sun Yat-sen University, Hospital of Stomatology, Sun Yat-sen University, Tianjin Medical University, China Medical University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,890
Awards: G3160146976, G3611014302, G4907004965
OpenAlex ID: W7125039996