Work

Analyses of the Effects of Wild‐Type TDP‐43 Overexpression in Oxytocin Neurons in Mice

Year: 2026

Type: article

Abstract: Selective TDP-43 overexpression in oxytocin neurons in the paraventricular nucleus of the hypothalamus causes a decrease in oxytocin-immunopositive cells compared to uninjected mice. AAV-mediated TDP-43 overexpression in oxytocin neurons does not appear to be a major driver of behavioural and metabolic phenotypes in mice.

Source: Neuropathology and Applied Neurobiology

DOI: 10.1111/nan.70059

Authors: Sofia Bergh, Oskar Simonsson, Åsa Petersén

Institutions: Lund University, Skåne University Hospital

Language: English

Topic: Neuroendocrine regulation and behavior

Subfield: Social Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,480