One-anastomosis gastric bypass vs sleeve gastrectomy for complications, perioperative status, and quality of life: Meta-analysis
Year: 2026
Type: article
Study designs: Systematic Review, Meta-Analysis
Abstract: BACKGROUND: One-anastomosis gastric bypass (OAGB) and sleeve gastrectomy (SG) are safe and effective bariatric surgeries. Literature assessing the complications, mortality, operative time/minutes, hospital stay/days, gastroesophageal reflux (GORD), malnutrition, and quality of life is scarce. AIM: To compare OAGB and SG regarding the above outcomes. METHODS: We searched 4 databases from inception up to July 2025. The keywords bariatric surgery, metabolic surgery, gastric bypass, SG, complications, perioperative, quality of life, operative time, hospital stay, GORD, malnutrition, and mortality were used. Out of 1163 studies retrieved, 54 full texts were reviewed, and 31 studies were included in the meta-analysis. RESULTS: No significant differences were evident between OAGB and SG regarding complications, odds ratio (OR), 1.37, 95% confidence interval (CI): 0.78-2.41. Operative time/minutes, hospital stay/days, and quality of life were similar between the two procedures, mean differences, 2.55, 95%CI: 3.61-8.70; -0.55, 95%CI: -1.12 to 0.02; and -0.37, 95%CI: -1.18 to 0.43 respectively, in sub-analyses including super-obesity and high diabetes, no significant differences were found regarding complications rate and operative time with higher hospital stay in patients with diabetes. Mortality and GORD were higher in SG, OR, 4.70, 95%CI: 1.64-13.52, and OR, 3.23, 95%CI: 1.56-6.72, while malnutrition was more common in OAGB, OR, 0.46, 95%CI: 0.36-0.59. CONCLUSION: There were no differences between OAGB and SG regarding complications, mortality, operation time/minutes, hospital stay/days, and quality of life. Mortality and GORD were higher in SG, while malnutrition was higher in OAGB. Further well-controlled trials comparing OAGB and SG regarding long-term outcomes are needed.
Author: Hyder Osman Mirghani
Institution: University of Tabuk
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7125185090