A case report: Masson’s tumor (intravascular papillary endothelial hyperplasia) of the abdominal cavity
Year: 2026
Type: article
Study design: Case Report
Abstract: Background: Masson's tumor, also known as intravascular papillary endothelial hyperplasia (IPEH), is a rare benign vascular lesion that can arise in a wide range of anatomical sites, most frequently within the dermis and subcutaneous tissues. Because its clinical manifestations and radiological appearances are nonspecific and may closely mimic those of malignant vascular neoplasms or soft-tissue sarcomas, it is frequently misinterpreted as a malignant tumor, particularly in the preoperative setting. To draw attention to this important diagnostic pitfall, we present a case of IPEH that was initially misdiagnosed as a malignant lesion, with the aim of improving recognition of its characteristic features and thereby enhancing diagnostic accuracy and reducing the likelihood of future misdiagnosis. Case Description: A 52-year-old woman was incidentally found to have a well-circumscribed, hypervascular intra-abdominal mass during a chest computed tomography (CT) scan. Magnetic resonance imaging showed a T1-hypointense/T2-hyperintense lesion with restricted diffusion and progressive enhancement. Given its marked hypervascularity and intra-abdominal location, a neoplastic process was initially suspected. However, following surgical exploration with complete excision of the mass and histopathological evaluation, the lesion was ultimately diagnosed as IPEH. Conclusions: Intra-abdominal Masson's tumor is exceedingly rare, and its imaging characteristics have not been systematically defined. In this report, we describe a surgically confirmed case of intra-abdominal Masson's tumor and place particular emphasis on its radiological features, including a well-circumscribed hyper vascular mass with progressive enhancement but without overt signs of malignancy. Despite these suggestive imaging findings, the definitive diagnosis continues to depend on histopathological assessment combined with immunohistochemical staining. By presenting this case, we hope to raise awareness of this benign yet deceptive vascular lesion and highlight that a pattern of progressive enhancement in the absence of malignant imaging features may prompt consideration of Masson's tumor in the differential diagnosis, thereby facilitating earlier and more accurate diagnosis.
Authors: Yiran Ren, Xiangrong Yu
Institutions: Jinan University, Zhuhai People's Hospital
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7125189084
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