Work

Distal Radial Access for Perimembranous Ventricular Septal Defect Closure

Year: 2026

Type: article

Abstract: BACKGROUND: Percutaneous perimembranous ventricular septal defect (pmVSD) closure traditionally uses femoral arterial access, which carries risks of vascular complications and prolonged bed rest. OBJECTIVE: We aim to report the first case series of pmVSD closure using distal radial access (DRA) with a single arterial retrograde approach. METHODS: Eight consecutive adult patients underwent percutaneous pmVSD closure via DRA using the Amplatzer Ductal Occluder II between 2018 and 2024 across 2 centers. All procedures used a single arterial access with a retrograde approach. RESULTS: Technical success was achieved in all patients (100%). The mean procedure time was 49.4 ± 7.3 minutes. Defect sizes ranged from 3 to 6 mm (right ventricle) and 5 to 6 mm (left ventricle). Complete closure occurred in all patients with no residual shunts at 1-year follow-up. No major complications occurred. CONCLUSIONS: DRA represents a safe, effective alternative for percutaneous pmVSD closure, offering reduced vascular complications, shorter hospital stays, and improved patient comfort compared with traditional femoral access.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.106563