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Figure 4 from Transcriptomic Analyses of Normal Human Pancreata Reveal the Presence of Cancer Subtypes that Correlate with Acinar Ductal Metaplasia and Donor Ancestry

Year: 2026
Type: other
Abstract: Validation of ADM indices in independent cohorts of normal pancreata. A, Supervised hierarchical clustering of ERT and C/B samples using the exocrine (Collisson), classical (Moffitt), and basal (Moffitt) subtype gene sets in the GSE183795 validation set. B, ADMIUp, (C) ADMIDown, (D) exocrine (Collisson), (E) classical (Moffitt), and (F) basal (Moffitt) as stratified by ERT and C/B subtype for NAT in the GSE183795 validation set. G, ADMIUp, (H) ADMIDown, (I) exocrine (Collisson), (J) classical (Moffitt), and (K) basal (Moffitt) stratified by ERT and C/B subtype and self-identified race in the GTEx validation cohort of 281 normal pancreata. Mean ± SD. Two-tailed Mann–Whitney U test. CPM, counts per million; RFU, relative fluorescent unit.
Subfield: Oncology
Field: Medicine
Open Access status: gold
OpenAlex ID: W7125262012
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