Work

Extracellular Vesicles in Gingival Crevicular Fluid as Indicators of Periodontitis and Early Response to Non‐surgical Periodontal Therapy

Year: 2026

Type: article

Abstract: Our study aims to profile EV subtypes and cytokines (IL-4, IL-10, IL-1β, TNF-α) across (1) shallow pockets (≤ 3 mm) in healthy, gingivitis, and periodontitis patients, and (2) deep pockets (≥ 6 mm) in periodontitis patients before and 1 month after NSPT. Preliminary data suggest that sEV-IL-4 and CD9+ sEV may reflect treatment response in periodontitis, being elevated in responding versus nonresponding sites.

Source: Journal of Periodontal Research

DOI: 10.1111/jre.70070

Authors: Pingping Han, Andrew Liaw, Akila Suboda Vithanage, Carlos Salomon, Sašo Ivanovski

Institutions: The University of Queensland, Royal Brisbane and Women's Hospital

Language: English

Topic: Oral microbiology and periodontitis research

Subfield: Periodontics

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: University of Queensland, Australian Dental Research Foundation, Metro North Hospital and Health Service