Work

A Novel Truncating Ep300 Mutation Impairs Intestinal Epithelial Differentiation in Patient Tissue and Organoids and Can Be Rescued by Chemical Hdac Inhibition

Year: 2026

Type: article

Study design: Case Report

Source: Inflammatory Bowel Diseases

DOI: 10.1093/ibd/izag006.146

Authors: Lauren Collen, Katlynn Bugda Gwilt, Michael Field, Maiya Whalen, Ashrita Iyengar, Lily Gillette, Geordie Emberling, Jeffrey Goldsmith, Scott Snapper, Jay Thiagarajah

Language: English

Topic: Genomics and Rare Diseases

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7125366337

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