Work

Exploring a Unique Class II Diterpene Cyclase: The Modified Catalytic Acid Motif Contributes to Ring Contraction in Premutilin Synthase

Year: 2026

Type: article

Abstract: -en-5β-ol-15-PP, providing insight into this unique reaction.

Source: Organic Letters

DOI: 10.1021/acs.orglett.5c04898

Authors: Kristin Helwig, Jun Xie, Cody Lemke, Meimei Xu, Xinye Kang, Meirong Jia, Reuben J. Peters

Institutions: Iowa State University, Chinese Academy of Medical Sciences & Peking Union Medical College

Language: English

Topic: Plant biochemistry and biosynthesis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: National Natural Science Foundation of China, National Institutes of Health, National Institute of General Medical Sciences

Awards: G3682587176, G6981119631, Investigating labdane-related diterpenoid biosynthesis

OpenAlex ID: W7125425270

FWCI: 1.822

Cites: 15

Cited by: 1

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