Sleep extension improves sleep health but not insulin sensitivity in people with overweight/obesity who maintain habitual short sleep schedules
Year: 2026
Type: other
Abstract: Objective: Determine whether extending sleep improves insulin sensitivity in people with overweight/obesity, insulin resistance, and habitual short-sleep schedules (<7h/night). Research Design and Methods: Participants were randomized to habitual sleep (HS; n=15) or extended sleep (ES; n=14) for ~6 weeks. Multi-organ (whole-body [primarily muscle], hepatic and adipose tissue) insulin sensitivity (assessed by the hyperinsulinemic-euglycemic clamp procedure with tracer infusions) and glycemic control (assessed by 24-h serial plasma glucose and insulin concentrations during wakefulness). Results: Time-in-bed and sleep duration increased more in the ES group (1.3±0.6 and 1.1±0.5 h/night) than the HS group (0.3±0.8 and 0.0±0.4 h/night). Day-to-day variability in sleep and subjective measures of sleep health improved more in the ES than HS group, without differences in multi-organ insulin sensitivity or glycemic control between groups. Conclusions: Extending sleep by ~1 h/night for ~6 weeks in people with overweight/obesity and short-sleep schedules improves sleep health but not insulin sensitivity or glycemic control.
Language: English
Topic: Sleep and related disorders
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: gold
OpenAlex ID: W7125523325
