Work

Emergence of Medetomidine in the Illicit Drug Supply: Implications for Emergency Care and Withdrawal Management

Year: 2026

Type: article

Abstract: The US illicit drug supply continues to evolve with increasingly dangerous adulterants, with medetomidine a new agent seen in acute care and other practice settings. We reviewed available literature on illicit drug adulterants, medetomidine intoxication, and sequelae. Although little is known about withdrawal and the clinical manifestations are stark, we reviewed the best available literature on dexmedetomidine withdrawal and suggest approaches for treatment.

Source: Annals of Emergency Medicine

DOI: 10.1016/j.annemergmed.2025.12.004

Authors: Michael J. Lynch, Anthony F. Pizon, Donald M. Yealy

Institution: University of Pittsburgh

Language: English

Topic: Poisoning and overdose treatments

Subfield: Emergency Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,850