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Abstract Th0028: Transcriptomic Dynamics of Mouse Arteriovenous Fistulas via Single-Cell RNA Sequencing Analysis

Year: 2026
Type: conference-abstract
Abstract: Arteriovenous fistula (AVF) is the preferred hemodialysis access for individuals with end-stage renal disease (ESRD); however, approximately 40% of AVFs fail to mature for hemodialysis without intervention. Despite this significant failure rate, our understanding of the cellular and molecular mechanisms underlying post-anastomosis vein remodeling remains limited. In this study, we present a detailed cellular atlas capturing the temporal changes in the mouse jugular vein following AVF anastomosis at the single-cell level.
Institution: University of Miami
Language: English
Open Access status: gold
Estimated APC paid: $2,800
OpenAlex ID: W7125614995
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