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Prime editing for ocular gene therapy and disease modeling: a narrative review of advances, delivery, and translational readiness

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Year: 2026
Type: review
Source: Experimental Eye Research
DOI: 10.1016/j.exer.2026.110891
Authors: Qing Zhang, Yanhui Yang, Xionggao Huang, Junkai Ma, Yajian Duan, Gaoen Ma, Hetian Lei
Institutions: Tongji University, Shanghai Tenth People's Hospital, Henan Medical University, Ningxia Medical University, Hainan Medical University, Shanxi Medical University, Shanxi Academy of Medical Sciences
Language: English

Topic: CRISPR and Genetic Engineering
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Health Commission of Shanxi Province, National Natural Science Foundation of China, Shanxi Scholarship Council of China, Natural Science Foundation of Ningxia Province, Shanxi Provincial Education Department
Awards: G4059196076, G4282586563, G5506802771, G6862166448, G6882149149
OpenAlex ID: W7125698051
FWCI:
Cites: 53
Cited by:
Related to: 10
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