Reconstruction of a Leaking Filtering Bleb after Trabeculectomy Using Amniotic Membrane Transplantation and Contralateral Conjunctival Autograft: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Purpose: To describe the successful reconstruction of a leaking filtering bleb with necrotic conjunctiva long after trabeculectomy, using a double-layer amniotic membrane transplantation (AMT) combined with a contralateral conjunctival autograft. Methods: A 63-year-old woman developed a thin, avascular, leaking bleb ten years after trabeculectomy with mitomycin-C. After infection control with fortified antibiotics, reconstruction was performed using AMT over the scleral flap, a contralateral conjunctival–Tenon autograft, and an additional AM patch. Results: The ocular surface healed uneventfully. At two months, the bleb was sealed with good filtration and stable intraocular pressure. Best-corrected visual acuity improved to 0.2 logMAR. Conclusion: The combined use of amniotic membrane and contralateral conjunctival autograft offers an effective solution for late-onset bleb leaks when local conjunctiva is friable.
Authors: Pablo Tejada González, Maria Dolores Díaz Barreda, Diana Pérez García, Javier Ramos Duarte, Francisco Javier Ascaso Puyuelo, Juan Ibáñez Alperte
Institution: Hospital Clínico Universitario Lozano Blesa
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7125939375
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