Work

Development of monoclonal antibodies for GoAstV-2 VP27 protein and precise mapping of linear antigenic epitopes

Year: 2026

Type: article

Abstract: was the minimal epitope recognized by mAb 11-39B. Homology and structural analyses demonstrated that the epitope was situated on the surface of the VP27 protein and exhibited high conservation among GoAstV-2 strains but exhibited significant differences in the GoAstV-1 serotype. Our study contributes to a better understanding of the GoAstV-2 VP27 antigenic region and provides a basis for establishing epitope-based GoAstV-2 diagnostic methods and vaccine development.

Source: Poultry Science

DOI: 10.1016/j.psj.2026.106535

Authors: Kaiyue Qin, Lingdan Yin, Huanrong Zhang

Institution: Southwest Minzu University

Language: English

Topic: Animal Virus Infections Studies

Subfield: Animal Science and Zoology

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,600