Year: 2026
Type: article
Abstract: The chick embryo chorioallantoic membrane (CAM) has long been a favored system for the study of tumor growth because a chick's immunocompetent system is not fully developed, and the conditions for rejection have not yet been established. Grafting tumors onto the CAM allows us to study the morphological aspects of the interactions of the tumors with the blood vessels of the host and to examine the identity of the vessels that supply the grafts. This article analyzes the literature data concerning the use of the CAM model to study lung cancer and the effects of anti-angiogenic molecules on the growth of this tumor due to the lack of literature data summarizing this topic.
Source: Frontiers in Oncology
Author: Domenico Ribatti
Institution: University of Bari Aldo Moro
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W7125978025