Work

Embedded point of care stratified block randomization: demonstration of the point of care randomization (POCR) engine with an electronic health record pragmatic clinical trial

Year: 2026

Type: preprint

Abstract: We describe a new custom feature within our Epic Systems electronic health record (EHR) that automates stratified randomization at the point-of-care or order. As a demonstration use-case, we conducted a randomized trial of a provider-facing alert for short-interval HbA1c orders. Over 3 months the alert dramatically reduced repeat orders. This transportable clinical informatics application transforms health systems' ability to conduct pragmatic clinical trials and deliver clinical care within the EHR.

Source: medRxiv

DOI: 10.64898/2026.01.26.26344847

Authors: Catherine Sarkisian, Khalda Ibrahim, Sitaram Vangala, Chad Wes Villaflores, Eric M. Cheng, William Turner, Richard K. Leuchter, Amy Machado, Julia Tabar, Jade A. Verdeflor, Jory Purvis, Alina Goncharova, Mark J. Pletcher

Institutions: University of California, Los Angeles, VA Greater Los Angeles Healthcare System, Greater Los Angeles Geriatric Research Education and Clinical Center, University of California, San Francisco

Language: English

Topic: Electronic Health Records Systems

Subfield: Health Information Management

Field: Health Professions

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7126035010

Cites: 8

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