Artificial Intelligence–derived Measurements of Myosteatosis from Coronary Artery Calcium CT Scans to Predict COPD: The Multi-Ethnic Study of Atherosclerosis
Year: 2026
Type: article
Study design: Observational Study
Abstract: Artificial intelligence–derived myosteatosis measurements from coronary artery calcium CT scans were strongly associated with the incidence of clinically diagnosed chronic obstructive pulmonary disease, outperforming emphysema-like lung as a predictive biomarker.
Source: Radiology Cardiothoracic Imaging
DOI: 10.1148/ryct.250205
Authors: Amir Azimi, Kyle Atlas, Anthony P. Reeves, Chenyu Zhang, Jakob Wasserthal, Seyed Reza Mirjalili, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Javier J. Zulueta, Juan P. de-Torres, Luis M. Seijo, Jeffrey I. Mechanick, Andrea Branch, Ning Ma, Rowena Yip, Wenjun Fan, Sion K. Roy, Khurram Nasir, Sabee Molloi, Zahi A. Fayad, Michael V. McConnell, Ioannis A. Kakadiaris, George S. Abela, Rozemarijn Vliegenthart, David J. Maron, Jagat Narula, Kim A. Williams, Prediman K. Shah, Matthew J. Budoff, Daniel Levy, Emelia J. Benjamin, Roxana Mehran, Robert A. Kloner, Nathan D. Wong, Morteza Naghavi
Institutions: Cornell University, University of Basel, Icahn School of Medicine at Mount Sinai, Clinica Universidad de Navarra, Universidad de Navarra, University of California, Irvine, The Lundquist Institute, Houston Methodist, Stanford Medicine, Stanford University, University of Houston, Michigan State University, University Medical Center Groningen, University of Louisville, Cedars-Sinai Medical Center, Boston University, Huntington Medical Research Institutes
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Awards: G1261793039, MESA, G1276754516, G1518934888, G1539384734, G1640378483, G1803853571, G1954818359, G2144938473, G22458031, MESA, G2580996367, MESA, G2837638605, G290884426, G291913881, SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READING, G3570589137, MESA, G408645584, TITLE: MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS (MESA), G4563812999, G4851331071, OPTION 3. 4/1/2014 - 3/31/2015. MULTI-ETHNIC STUDY OF ATHEROSCLEROSIS (MESA) - READING CENTER, NHLBI, MESA, G5108002584, Deriving Bone Density from Thoracic CT Scans, STTR Phase II, G514410172, SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-ULTRASOUND, Institute for Clinical and Translational Research, MESA, G66341962, MESA, G78770644, Clinical and Translational Science Award, G8761005068, G94668252, G991334795
OpenAlex ID: W7126051202