XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (II)
Year: 2026
Type: article
Abstract: INTRODUCTION: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists specialized in multiple sclerosis (MS), who presented a summary of the most relevant advances discussed at the ECTRIMS congress, held days before in Copenhagen. AIM: To summarize the main new findings in clinical research on MS. Content and Conclusions: The immunological changes throughout life and in response to MS treatments were analyzed. The impact of aging was also discussed, along with new developments related to symptomatic treatments, physical exercise, fatigue, and sleep disorders. Emphasis was placed on addressing ongoing challenges in measuring therapeutic failure and managing treatments for secondary progressive MS. Additionally, data from registries and real-world studies were presented, including new analyses on cladribine, highlighting the need to collect safety information. Regarding immune reconstitution therapies, mechanisms of action and the immune system's reconstitution process after treatment were explored. Finally, regarding therapeutic innovations, the first results from chimeric antigen receptor (CAR)-T cell therapy studies in MS were reported, representing a promising advancement in disease management.
Source: Revista de Neurología
DOI: 10.31083/rn39228
Authors: Óscar Fernández, Adrián Arés, Eduardo Agüera, Yolanda Aladro, Ana Alonso, Rafael Arroyo, Luis Brieva, Carmen Calles, Ana Belén Caminero, Tamara Castillo-Triviño, Lucienne Costa-Frossard, Sara Eichau, Miguel Ángel Hernández, Lamberto Landete, Miguel Llaneza, Sara Llufriu, José E. Meca-Lallana, Virginia Meca-Lallana, Ester Moral, Celia Oreja-Guevara, José María Prieto, Lucía Romero-Pinel, Andreu Vilaseca, Alfredo Rodríguez-Antigüedad
Institutions: Hospital Regional Universitario de Málaga, Instituto de Investigación Biomédica de Málaga, Universidad de Málaga, Complejo Asistencial Universitario de León, Hospital Universitario Reina Sofía, Hospital Universitario de Getafe, Hospital Universitario Quirónsalud Madrid, IDCQ Hospitales y Sanidad, S.L.U., Universitat de Lleida, Hospital Universitari Arnau de Vilanova, Hospital Universitario Son Espases, Biogipuzkoa Health Research Institute, Donostiako Unibertsitate Ospitalea, Hospital Universitario Ramón y Cajal, Hospital Universitario Virgen Macarena, Hospital Universitario Nuestra Señora de Candelaria, Hospital Universitario Doctor Peset, Hospital Universitario Central de Asturias, Hospital Clínic de Barcelona, Consorci Institut D'Investigacions Biomediques August Pi I Sunyer, Instituto Murciano de Investigación Biosanitaria, Hospital Universitario Virgen de la Arrixaca, Universidad Católica de Murcia, Hospital Universitario de La Princesa, Hospital de Sant Joan Despí Moisès Broggi, Universidad Complutense de Madrid, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Instituto de Investigación Sanitaria de Santiago, Bellvitge University Hospital, Institut d'Investigació Biomédica de Bellvitge, Vall d'Hebron Hospital Universitari, Centre d'Esclerosi Múltiple de Catalunya, Hospital de Cruces
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funder: Merck
OpenAlex ID: W7126074007