Work

Enhancing adoptive T cell therapy by disrupting the SKI-SMAD2/3 axis to counteract TGF-β-mediated immunosuppression

Year: 2026

Type: article

Source: Molecular Therapy

DOI: 10.1016/j.ymthe.2026.01.028

Authors: Xiaohan Jin, Jingxuan Yu, Xinyu Wu, Qingyong Hu, Xixi Chen, Wenbo Ma, Yude Guan, Dongmei Guo, Yulan Yang, Lingyu Wang, Guofei Jin, Zhenglan Han, Shumin Zhang, Nianchao Zhang

Institutions: North Sichuan Medical University, Tianjin University of Traditional Chinese Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences, Nankai University

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Natural Science Foundation of China

Awards: G3187527026, G6686502915

OpenAlex ID: W7126079863

FWCI: 2.93

Cites: 32

Cited by: 1

Related to: 10