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YBX1 promotes angiogenesis after myocardial infarction by stabilizing HIF1α mRNA via m6A signaling

Year: 2026

Type: article

Abstract: A-dependent IGF2BP1/3-HIF1α axis, establishing YBX1 as a therapeutic target for ischemic heart disease.

Source: iScience

DOI: 10.1016/j.isci.2026.114810

Authors: Fangfang Bi, Tong Yu, Hanyu Liu, Miao Cao, Yijie He, Jin Li, Haoshu Wang, Chengyu Kong, Hongwen Xiao, Hua Tian, Fu Liu, Yun Wu, Yuhong Zhou, Hongli Shan

Institutions: Harbin Medical University, Fourth Affiliated Hospital of Harbin Medical University, Shanghai University of Engineering Science, Xi'an Jiaotong University, Second Affiliated Hospital of Harbin Medical University, Xiamen Medical College

Language: English

Topic: RNA modifications and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: Harbin Medical University, Natural Science Foundation of Xiamen City, National Natural Science Foundation of China, Department of Education, Fujian Province

Awards: G3616912773, G3965715988, G7474004769, G8539244170, G8720181784

OpenAlex ID: W7126087558

FWCI: 1.939

Cites: 35

Cited by: 1

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