Investigation of targeted bioactive compounds in selected chinese herbal liquors by HPLC-ESI-MS/MS
Year: 2026
Type: article
Abstract: In this study, a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was developed for the simultaneous determination of 24 active constituents (including dihydromyricetin, rutin, glycyrrhizic acid, etc.) in herbal liquors, which are globally consumed but lacks systematic research on its composition and content. Method validation demonstrated limits of detection (LOD) of 0.1–50 ng/mL, intra-day precision (RSD) <6.32%, and recovery rates of 88.7–99.4%. Analysis of 41 commercial samples revealed component concentrations spanning 0.000868–155 ng/mL, with 66% containing 3–8 active ingredients and exhibiting distinct compositional gradients. This study proposes a three-tier quality control (QC) system for herbal liquor based on an integration of traditional compatibility theory and modern demand stratification. The valuable information regarding the concentrations of these bioactive constituents in herbal liquor is crucial for quality assessment and may serve as guidance for the development of new herbal products.
Source: Applied Food Research
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,050
OpenAlex ID: W7126092065