Work

Discovery of Novel Orally Bioavailable Polθ Inhibitors with Arylalkyne Scaffolds for Targeting HR-Deficient Cancers

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c01977

Authors: Jinyang Zhang, Xiaomeng Sun, Qichen Zhou, Yingying Wei, Biao Chen, Junhui Jiao, Yu Du, Shepherd Wufoyrwoth, Haoze Chi, Yi Yang, Ping Wei, Yungen Xu, Yi Zou, Qihua Zhu

Institutions: China Pharmaceutical University, State Key Laboratory of Natural Medicine

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7126180494

FWCI: 2.778

Cites: 39

Cited by: 1

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