Strategic Use of Benzylic Alcohols Reveals Cryptic Hydrogen-Bonding Interactions: Discovery of HBC-12551 as a Potent Noncovalent Bruton’s Tyrosine Kinase Inhibitor
Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
Authors: Gang Liu, Shuaishuai Liu, Sangwoo Cho, Hee-Don Chae, Wei Zhou, Lingtian Zhang, Avinash Khanna, Xin Zeng, Xinlin Du, Hugh Zhu, Tzu-Pei Chang, Nathan Max, Megha Kumar, Cynthia Chen, Lance Lee
Institution: Hansoh Bio (United States)
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: closed
OpenAlex ID: W7126185178