The fate of the Fontan circulation
Year: 2025
Type: article
Abstract: Since the first operation performed in 1968, the worldwide population of patients living with Fontan circulation is dramatically growing, with 40% reaching adulthood in the current era. Despite this remarkable improvement in survival, some patients struggle with Fontan-related complications including heart failure, arrhythmias, end-organ dysfunction, and premature death. This review aims at describing common complications of the Fontan circulation, proposing a clinical and mortality risk score to better stratify this complex population as well as exploring the current state of art in catheter interventions and transplant.
Institutions: Ospedale Monaldi, Bambino Gesù Children's Hospital, Istituti di Ricovero e Cura a Carattere Scientifico, Imperial College London, Hôpital Marie Lannelongue, Erasmus MC, Universidad Complutense de Madrid, Hospital General Universitario Gregorio Marañón, Centro de Investigación en Red en Enfermedades Cardiovasculares, Instituto de Investigación Sanitaria Gregorio Marañón, Queen Elizabeth Hospital Birmingham, Universitair Ziekenhuis Leuven, KU Leuven, University of Rijeka, Guy's and St Thomas' NHS Foundation Trust, Harefield Hospital, Royal Brompton Hospital
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7126199245