Work

Hepatic plexiform neurofibroma a rare manifestation of neurofibromatosis type 1: A case report and literature review

Year: 2026

Type: article

Abstract: Neurofibromatosis type 1 (NF1) is a clinical diagnosis supported by characteristic radiological multisystem manifestations. NF1 commonly presents with cutaneous, musculoskeletal, and neurological findings, while abdominopelvic involvement is less frequent. We present the case of a 7-year-old girl clinically and radiologically diagnosed with NF1 who was incidentally found to have a hepatic lesion. Further investigations confirmed a hepatic plexiform neurofibroma, a rare manifestation of NF1 with few reported cases worldwide. This report describes the patient's neurological findings, as well as the sonographic, cross-sectional, and magnetic resonance imaging features of hepatic plexiform neurofibroma.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.12.011

Authors: Omar Y. Alkhaja, Feras Shmeylan Alharbi, Mohammed Salem Wadani, Moayad Khalid Almaimani, Ahmed Aldraihem

Institution: King Fahd Medical City

Language: English

Topic: Neurofibromatosis and Schwannoma Cases

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600