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Toxic epidermal necrolysis in a preschooler associated with adenovirus respiratory infection: A case report

Year: 2026

Type: article

Abstract: Toxic epidermal necrolysis (TEN) is a rare, life threatening mucocutaneous disorder characterized by widespread epidermal necrosis and detachment, typically classified as a type IVc hypersensitivity reaction mediated by cytotoxic T lymphocytes.1,2 TEN represents the most severe form within the Stevens–Johnson syndrome (SJS)/TEN spectrum. The classification is based on the extent of epidermal detachment where SJS involves less than 10% of the body surface area, SJS/TEN overlap 10% to 30%, and TEN exceeds 30%.

Source: JAAD Case Reports

DOI: 10.1016/j.jdcr.2026.01.030