Associations between dentition status and cardiometabolic disease in adults: a cross-sectional analysis
Year: 2026
Type: article
Study design: Observational Study
Abstract: Objectives: This study explored associations between dentition status and cardiometabolic diseases in adults. Materials and methods: Cross-sectional analysis was conducted using data from adults receiving routine care at an urban US Dental School clinic between January 1, 2020, and June 1, 2023. Associations between dentition status (measured by tooth loss and functional dentition [FD] status) and cardiometabolic diseases (diabetes mellitus [DM], hypertension [HTN], stroke, and cardiovascular disease [CVD]) were explored using binary logistic regression models while controlling for cardiometabolic risk factors [CMRFs]. Results: = 32,541) was 67.6% 40 years or older, 54.1% female, 51.7% White/Caucasian, 41.7% Black, 70.3% non-Hispanic/non-Latino, 69.6% overweight/obese; 16.0% reported tobacco use. The median number of remaining teeth was 26.0; 75.7% had FD. After adjusting for CMRFs, each additional tooth was associated with lower odds of DM (OR = 0.98, 95% CI = 0.98, 0.99), HTN (OR = 0.98, 95% CI = 0.98, 0.99), stroke (OR = 0.97, 95% CI = 0.96, 0.98), and CVD (OR = 0.97, 95% CI = 0.97,0.98). FD was associated with lower odds of DM (OR = 0.77, 95%CI = 0.70,0.84), HTN (OR = 0.78, 95% CI = 0.72, 0.850), stroke (OR = 0.65, 95% CI = 0.55,0.77), and CVD (OR = 0.71, 95% CI = 0.63-0.79). After adjusting for comorbid cardiometabolic conditions, having more teeth remained associated with lower odds of DM (OR = 0.99, 95% CI = 0.98, 0.99), HTN (OR = 0.99, 95% CI = 0.98, 1.00), and CVD (OR = 0.98, 95% CI = 0.97, 0.99). FD was associated with lower odds of DM (OR = 0.82, 95% CI = 0.68-0.92), HTN (OR = 0.84, 95% CI = 0.77, 0.92), and CVD (OR = 0.81, 95% CI = 0.71, 0.93). Conclusion: Tooth retention is associated with lower odds of having cardiometabolic disease. Enhanced knowledge and awareness of these associations can lead to improved cardiometabolic risk screening in interprofessional settings.
Source: Frontiers in Oral Health
Institutions: Rutgers, The State University of New Jersey, Rutgers Health
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,077
OpenAlex ID: W7126257478
