Work

Discovery of Novel Natural Product-Based PDE4 Inhibitors for Ischemic Stroke Treatment without Emetogenicity at Ultra-High Doses

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02951

Authors: Chuang Xia, Mingjia Yu, Yujie Ni, Shanfang Fang, Kaiwen Feng, Tingting Zhang, Chunping Gu, Kaibin Huang, Zhong-Zhen Zhou

Institutions: Southern Medical University, Nanfang Hospital

Language: English

Topic: Phosphodiesterase function and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province

Awards: G2125358882, G3409209731, G5173877154, G6785682678

OpenAlex ID: W7126270180

FWCI:

Cites: 33

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