Year: 2026
Type: article
Abstract: This review provides a comprehensive analysis of Amarogentin (AMA), a secoiridoid glycoside from the Gentianaceae family, highlighting its significant pharmacological effects. AMA demonstrates liver protection, anticancer, anti-inflammatory, antioxidant and antibacterial properties. Pharmacokinetic studies show rapid elimination and wide distribution of AMA in the body. Toxicity research indicates low toxicity to most cell types, although long-term and high-dose animal toxicity data are lacking. The therapeutic potential of AMA for liver fibrosis, cancer and diabetes is promising but further research is needed to explore its mechanisms, targets, toxicity and enhance oral bioavailability.
Author: Ying Tan
Institution: Chongqing Three Gorges Medical College
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W7126428536
FWCI:
Cites:
Cited by:
Related to: