Succinate is an inflammatory signal that induces IL-1β through HIF-1α
Year: 2013
Type: article
Source: Nature
DOI: 10.1038/nature11986
Authors: G. M. Tannahill, A. M. Curtis, J. Adamik, E. M. Palsson-McDermott, A. F. McGettrick, G. Goel, C. Frezza, N. J. Bernard, B. Kelly, N. H. Foley, L. Zheng, A. Gardet, Z. Tong, S. S. Jany, S. C. Corr, M. Haneklaus, B. E. Caffrey, K. Pierce, S. Walmsley, F. C. Beasley, E. Cummins, V. Nizet, M. Whyte, C. T. Taylor, H. Lin, S. L. Masters, E. Gottlieb, V. P. Kelly, C. Clish, P. E. Auron, R. J. Xavier, L. A. J. O’Neill
Institutions: Trinity College Dublin, Duquesne University, Massachusetts General Hospital, Center for Computational and Integrative Biology, Massachusetts General Hospital, MRC Cancer Unit, Hutchison/MRC Research Centre, Cancer Research UK Scotland Institute, Medical Research Council, Broad Institute, Cornell University, University of Sheffield, University of California System, University College Dublin, Walter and Eliza Hall Institute of Medical Research
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
Awards: Boosting Innate Immunity Through HIF to Treat Antibiotic-Resistant Infections, Boosting Innate Immunity Through HIF to Treat Drug-Resistant Bacterial Infections, Regulation of neutrophilic inflammation by the HIF/PHD pathway., Molecular Analyses and Interventions for Biodefense and Emerging Pathogens
OpenAlex ID: W2089532303