Work

Accelerated Diffusion Basis Spectrum Imaging With Tensor Computations

Year: 2026

Type: article

Abstract: This paper introduces an advanced framework for accelerated processing of diffusion-weighted imaging (DWI) data that utilizes an entire-image modeling approach to optimize the estimation of diffusion parameters from DWIs by mapping input diffusion data to predicted signals and estimating parameter values via a stochastic gradient descent optimizer (Adam). To validate this approach, we applied this framework to diffusion basis spectrum imaging (DBSI) and analyzed in vivo human brain and ex vivo mouse brain DWIs. Results demonstrate significant improvements to computational speed and signal-to-noise ratio (SNR) in estimated parameter maps compared to standard DBSI. Our approach is applicable to any diffusion signal representation and enables rapid and reliable signal partitioning in complex microstructural environments, demonstrating the potential of this framework for future neuroimaging research.

Source: Human Brain Mapping

DOI: 10.1002/hbm.70460

Authors: Kainen L. Utt, Jacob S. Blum, Donsub Rim, Sheng‐Kwei Song

Institution: Washington University in St. Louis

Language: English

Topic: Advanced Neuroimaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $3,520

Funder: National Institutes of Health