Work

Neonatal Seizure Detection Based on Spatiotemporal Feature Decoupling and Domain-Adversarial Learning

Year: 2026

Type: article

Abstract: Neonatal seizures are a critical early indicator of neurological injury, yet effective automated detection is challenged by significant inter-subject variability in electroencephalogram (EEG) signals. To address this generalization gap, this study introduces the Domain-Adversarial Spatiotemporal Network (DA-STNet) for robust cross-subject seizure detection. Utilizing Short-Time Fourier Transform (STFT) spectrograms, the architecture employs a hierarchical backbone comprising a Channel-Independent CNN (CI-CNN) for local texture extraction, a Spatial Bidirectional Long Short-Term Memory (Bi-LSTM) for modeling topological dependencies, and Attention Pooling to dynamically prioritize pathological channels while suppressing noise. Crucially, a Gradient Reversal Layer (GRL) is integrated to enforce domain-adversarial training, decoupling pathological features from subject-specific identity to ensure domain invariance. Under rigorous 5-fold cross-validation, the model achieves State-of-the-Art performance with an average Area Under the Curve (AUC) of 0.9998 and an F1-score of 0.9952. Data scaling experiments further reveal that optimal generalization is attainable using only 80% of source data, highlighting the model's superior data efficiency. These findings demonstrate the proposed method's capability to reduce reliance on extensive clinical annotations while maintaining high diagnostic precision in complex clinical scenarios.

Source: Sensors

DOI: 10.3390/s26030938

Authors: Tiannuo Xu, Wei Zheng

Institution: Jiangsu University of Science and Technology

Language: English

Topic: EEG and Brain-Computer Interfaces

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137