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Rare Event: Neonatal Anaphylaxis Following Hepatitis B Vaccination – A Case Series from a Tertiary Care Center in India

Year: 2026
Type: article
Study design: Case Report
Abstract: We report two cases of anaphylaxis following Hepatitis B vaccination in one-day-old neonates at a tertiary care hospital in India. Both cases presented with similar patterns of cutaneous reactions and respiratory symptoms shortly after intramuscular administration of the Hepatitis B vaccine. To our knowledge, this is among the few documented case series of neonatal anaphylaxis post–Hepatitis B vaccination, underscoring its rarity yet clinical importance. The cases highlight the critical importance of vigilant post-vaccination monitoring and prompt recognition of vaccine-associated adverse events in neonates. This report reviews current literature on anaphylaxis following vaccination and discusses optimal management strategies.
Language: English
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W7127090752
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