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LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver (Adv. Mater. 7/2026)

Year: 2026

Type: article

Abstract: Fat-Clearing Nanoplatform In the Research Article by Dae Won Jun, Jinyoung Park, Hyunbeom Lee, Joonseok Lee, and co-workers (DOI: 10.1002/adma.202506373), a dual-functional lipid droplet inhibitor integrates two biomolecules onto a porous nanostructure, enabling lipid capture and enzymatic breakdown, while the Pickering emulsion effect enhances droplet stability and lipid management. The platform reduces liver fat and restores lipid balance in a fatty liver mouse model.

Source: Advanced Materials

DOI: 10.1002/adma.72127

Authors: Seunghee Kim, Yeojin Kim, Sanjita Paudel, In Young Kang, Suyeon Kim, Jeesoo Kim, Sunmi Park, Seung‐Hoi Koo, Hyun Sung Kim, Dae Won Jun, Jinyoung Park, Hyunbeom Lee, Joonseok Lee

Institutions: Hanyang University, Korea University, Korea Institute of Science and Technology

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W7127100684

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