Work

Isolated Iridium Active Sites in Metal–Organic Frameworks for Selective Hydrogenation of Nitroaromatics

Year: 2026

Type: article

Abstract: A robust metal–organic framework (MOF) catalyst featuring site‐isolated Ir centers, UiO‐67‐Pyma‐Ir, is reported for selective hydrogenation of nitroaromatics under mild conditions. UiO‐67‐Pyma‐Ir exhibits exceptional chemoselectivity by preferentially catalyzing the hydrogenation of nitro groups to amino groups in the presence of potentially susceptible functional groups such as carbonyl (CO), alkene (CC), and halogen substituents, enabling high conversion of nitroarenes while retaining the integrity of sensitive functional motifs. UiO‐67‐Pyma‐Ir also demonstrates high stability and recyclability as its activity and structural integrity is maintained over six consecutive cycles without significant degradation. This work provides a sustainable strategy for the synthesis of functionalized anilines with promising potential in fine chemical and pharmaceutical manufacturing.

Source: Advanced Synthesis & Catalysis

DOI: 10.1002/adsc.70290

Authors: Wang‐Lan Xu, Ji‐Min Ouyang, Jun‐Yu Li, Teng Zhang

Institutions: Fujian Normal University, Chinese Academy of Sciences, Fujian Institute of Research on the Structure of Matter, University of Chinese Academy of Sciences, State Key Laboratory of Structural Chemistry

Language: English

Topic: Metal-Organic Frameworks: Synthesis and Applications

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funder: National Natural Science Foundation of China

Awards: G7105059420, G8954353494