Work

Ultrasound-based computational fluid dynamics analysis of carotid artery hemodynamics in healthy and stenosed conditions

Year: 2026

Type: article

Abstract: Atherosclerosis in the carotid arteries increases stroke risk, yet current treatment decisions rely mainly on stenosis degree, which poorly reflects individual vulnerability. We present an ultrasound-based computational fluid dynamics (CFD) framework for patient-specific hemodynamic assessment. Using tracked 2D ultrasound and automated segmentation, we reconstructed carotid geometries for five healthy subjects and three patients with severe stenoses. CFD simulations quantified TAWSS, OSI, RRT, and helicity, visualized through risk maps. Healthy arteries showed localized risk near bifurcations, whereas stenosed geometries exhibited extensive disturbed flow and altered helicity patterns. This approach demonstrates the feasibility of ultrasound-driven CFD for personalized risk mapping and highlights helicity's potential as a diagnostic marker.

Source: Computer Methods in Biomechanics & Biomedical Engineering

DOI: 10.1080/10255842.2026.2617934

Authors: Lotte Piek, Milan Gillissen, Joerik de Ruijter, Marc van Sambeek, Richard Lopata

Institutions: Catharina Ziekenhuis, Eindhoven University of Technology

Language: English

Topic: Cerebrovascular and Carotid Artery Diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Toegepaste en Technische Wetenschappen, NWO, Nederlandse Organisatie voor Wetenschappelijk Onderzoek