Work

Trends in Chronic Ischemic Heart Disease‐Related Mortality in Older Adults With Atrial Fibrillation (1999–2023): A CDC WONDER Database Analysis

Year: 2026

Type: article

Abstract: INTRODUCTION: Atrial fibrillation (AF) is the most common and persistent type of arrhythmia that frequently co-exists with chronic ischemic heart disease (IHD), increasing the risk of adverse cardiovascular outcomes and mortality. We aim to analyze chronic IHD-related mortality trends in patients with AF from 1999 to 2023 in the United States (U.S.). METHODS: Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database was used to conduct a retrospective analysis of death records of adults (aged 65 ≤) with chronic IHD as the underlying cause and co-existent AF as a contributing cause of death. Age-adjusted mortality rates (AAMR) per 100 000 population and annual percent changes (APC) in age-adjusted mortality rates were determined and measured across different demographics and geographies in the U.S. RESULTS: AF was recorded in almost 460,196 deaths caused by chronic IHD. The AAMR increased from 38.2 in 1999 to 52.2 in 2023, showing a prominent increase shift from 2010 to 2023 (APC: 2.72). Recorded AAMR in Males (54.8) was doubled that of females (33.2), while a top AAMR of 44.7 was seen in non-Hispanic (NH) Whites was doubled that of other racial/ethnic groups. Geographically, AAMR was higher in non-metropolitan areas (43.3) and the Northeast region (42.8). CONCLUSIONS: Proper resource distribution and more targeted interventions are needed to address the rising trends in chronic IHD mortality among AF patients across different geographic and demographic groups.

Source: Clinical Cardiology

DOI: 10.1002/clc.70267

Authors: Muhammad Shaheer Bin Faheem, Syed Tawassul Hassan, Tehreem Asghar, Nafila Zeeshan, Sumaya Samadi

Institutions: Karachi Medical and Dental College, Akhtar Saeed Medical and Dental College, Dow University of Health Sciences, Kabul University of Medical Sciences Abu Ali Ibn Sina

Language: English

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,810