Year: 2026
Type: report
Study design: Systematic Review
Abstract: a t u re o n e x e rc i s e interventions on primary brain tumor patient-caregiver dyads.Background Primary malignant brain tumors (PBT) impose substantial burdens on patients and caregivers.Caregivers are essential in the delivery of outpatient care for patients with PBT but experience high levels of fatigue, distress, and health decline.While exercise is known to improve outcomes in cancer patients, interventions tailored specifically to the PBT patient-caregiver dyad remain limited.Dyadic intervention as well as exercise oncology are emerging areas of active research in neuro-oncology.This scoping review incorporates both principles to evaluate the existing literature on exercise interventions on primary brain tumor patient-caregiver dyads.Rationale Dyadic intervention as well as exercise oncology are emerging areas of active research in neuro-oncology.This scoping review incorporates both principles to evaluate the existing literature on exercise interventions on primary brain tumor patient-caregiver dyads. METHODS Strategy of data synthesisWe conducted a comprehensive search of MEDLINE ( PubMed), Embase, CINAHL (EBSCO), Rehabilitation & Sports Medicine (EBSCO), and Cochrane Central (Ovid) in December 2025 for studies involving exercise interventions that included adult PBT patients and caregivers.Risk of bias was assessed using the G R A D E ( G r a d i n g o f R e c o m m e n d a t i o n s Assessment, Development, and Evaluation) framework.Eligibility criteria We conducted comprehensive searches of MEDLINE (PubMed), Embase, CINAHL (EBSCO), Rehabilitation & Sports Medicine (EBSCO), and Cochrane Central (Ovid) on
Authors: Anh Huan Vo, Maximilian Libmann, David Carson, Kimberly Wang, Sushant Puri, Nicholas Butowski, Kerri Winters-Stone
Topic: Cancer survivorship and care
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7127429429
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