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Endovascular intervention and therapeutic plasma exchange in the treatment of cerebral venous thrombosis associated with thyrotoxicosis: illustrative case

Year: 2026

Type: article

Abstract: BACKGROUND: Cerebral venous thrombosis (CVT) is a rare cerebrovascular disorder that predominantly affects younger individuals. Its development is influenced by multiple factors, including hypercoagulability, hemodynamic abnormalities, and venous vessel wall injury. Thyrotoxicosis is an uncommon but increasingly recognized predisposing factor for CVT. OBSERVATIONS: The authors present the case of a young female with thyrotoxicosis-induced CVT who achieved successful recovery following endovascular intervention and therapeutic plasma exchange (TPE). LESSONS: This report emphasizes the clinical importance of recognizing thyrotoxicosis as a risk factor for CVT, underscores the therapeutic potential of TPE in thyroid storm complicated by thrombosis, and provides clinical reference for endovascular intervention in the treatment of CVT. https://thejns.org/doi/10.3171/CASE25820.

Source: Journal of Neurosurgery Case Lessons

DOI: 10.3171/case25820

Authors: Rui Zhou, Qinghua Luo, Shenjian Chen, Zhiyong Sheng, Wei Huang

Institutions: Second Affiliated Hospital of Nanchang University, Second Hospital of Nanchang

Language: English

Topic: Cerebral Venous Sinus Thrombosis

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7127444625

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